Neurotransmitter systems

Probably everyone who have studied some physiology have heard of the neurotransmitters, but the systems of those neurotransmitters weren’t familiar to me. With this topic, based on the book it was a bit difficult to form understanding of the whole picture. However, the lecture offered more help with understanding the relationships with the subtopics of the chapter.

The most interesting takeaway of the chapter was the introduction of the methods to study the transmitter receptors. I find it interesting, how these different receptors have been identified with neuropharmacological analysis of synaptic transmission, ligand-binding methods, and molecular analysis of receptor proteins. However, the molecular analysis of the receptor proteins was left a bit unclear to me. What the analysis covers and how they are using the knowledge gained from the analysis.

Overall this chapter was challenging due to the intense content of the transmitter synthesis for different transmitters. I had difficulties in internalizing how the systems work between different transmitters. It was also more difficult to answer to the quiz as it was really difficult to remember all the content from reading the chapter.

Which consequences are related to lack of production of each of the transmitters? For example, lack of dopamine has been proven to relate to Parkinson’s disease.

As the book mentioned that one of the most interesting findings during past few years have been the endocannabinoids, what are the potential findings or functions related to endocannabinoids that researches are hoping to find addition to existing knowledge?

Is there any signal cascades in other receptors than the G-protein-coupled receptors?

-Erika

Posted by Erika Ojanperä

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