From the point of view of a student, the world of neurotransmitters and receptors is full of wonders and big questions. How many types or subtypes of reseptors we haven’t found yet? Could a solution to some of the problematic brain diseases lie in some undiscovered receptor? Could we still find new pain relieving or sedating molecules based on GABA agonism?
If from approximately 100 of known neurotransmitters ten do most of the work, how many effects or possibilities are hidden in the lesser known ones? What would happen if we altered these rarer neurotransmitters and how would they work after it or would they function at all. How many possible receptor agonists or antagonist are still unfound somewhere in nature?
With my background in pharmacy I cannot help thinking, about all the possible opportunities for neurodisease treatment we could still find in neuroreseptors.
When studying neuronal impulses and how they travel via electric impulses and chemical neurotransmitters, I rarely stop to think how fast they actually travel. Sure I have calculated the speed as an exercise, but it is hard to truly understand the sheer speed of impulses untill you do a reaction time test.
Imagine it, you see a shape or hear a sound and it takes only around 200-300 ms to react, not to mention the speed at which you react to pain. Feels like you react faster than you even feel the pain. At that short time, impulses have travelled a long distance and chemical neurotransmitters have . The idea is overwhelming.